PDBsum entry 3fk2

Signaling protein, hydrolase activator

PDB id: 3fk2

Contents

Protein chains

196 a.a. *

Ligands

UNX ×8

* Residue conservation analysis

PDB id:

3fk2

Name:

Signaling protein, hydrolase activator

Title:

Crystal structure of the rhogap domain of human glucocorticoid receptor DNA-binding factor 1

Structure:

Glucocorticoid receptor DNA-binding factor 1. Chain: a, b, c, d. Fragment: unp residues 1212-1439. Synonym: glucocorticoid receptor repression factor 1, grf-1, rho gap p190a, p190-a. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: grlf1, grf1, kiaa1722. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: the authors suspect that the sample was truncated by in-situ proteolysis.

Resolution:

2.80Å R-factor: 0.226 R-free: 0.273

Authors:

L.Nedyalkova,Y.Tong,W.Tempel,P.Loppnau,C.H.Arrowsmith,A.M.Edwards, C.Bountra,J.Weigelt,A.Bochkarev,H.Park,Structural Genomics Consortium (Sgc)

Key ref:

L.Nedyalkova et al. Crystal structure of the rhogap domain of human glucocorticoid receptor DNA-Binding factor 1. To be published, .

Date:

15-Dec-08 Release date: 23-Dec-08

Protein chains

Q9NRY4  (RHG35_HUMAN) -  Rho GTPase-activating protein 35 from Homo sapiens

Seq: 1499 a.a.

Struc: 196 a.a.