UniProt functional annotation for P23280

UniProt code: P23280.

Organism: Homo sapiens (Human).
Taxonomy: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
 
Function: Reversible hydration of carbon dioxide. Its role in saliva is unknown.
 
Catalytic activity: H(2)CO(3) = CO(2) + H(2)O.
Cofactor: Zinc (By similarity).
Enzyme regulation: Inhibited by coumarins, sulfonamide derivatives such as acetazolamide (AZA), saccharin and Foscarnet (phosphonoformate trisodium salt).
Subcellular location: Secreted.
Tissue specificity: Major constituent of saliva.
Similarity: Belongs to the alpha-carbonic anhydrase family.

Annotations taken from UniProtKB at the EBI.