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PDBsum entry 3euu
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* Residue conservation analysis
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PDB id:
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Transferase
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Title:
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Crystal structure of the fgfr2 d2 domain
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Structure:
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Fibroblast growth factor receptor 2. Chain: a, b. Fragment: unp residues 150-249. Synonym: fgfr-2, keratinocyte growth factor receptor 2. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: fgfr2, bek, kgfr, ksam. Expressed in: escherichia coli. Expression_system_taxid: 562
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Resolution:
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2.34Å
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R-factor:
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0.186
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R-free:
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0.228
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Authors:
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J.Sakon,F.Guo,R.Dakshinamurthy,K.M.Kathir,S.K.K.Thallapuranam
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Key ref:
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F.Guo
et al.
Crystal structure of the d2 domain of hfgfr2.
To be published,
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Date:
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10-Oct-08
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Release date:
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25-Aug-09
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PROCHECK
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Headers
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References
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P21802
(FGFR2_HUMAN) -
Fibroblast growth factor receptor 2 from Homo sapiens
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Seq: Struc:
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821 a.a.
100 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.2.7.10.1
- receptor protein-tyrosine kinase.
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Reaction:
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L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H+
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L-tyrosyl-[protein]
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+
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ATP
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=
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O-phospho-L-tyrosyl-[protein]
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+
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ADP
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+
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H(+)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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}
}
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