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UniProt functional annotation for Q92882 | ||
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| UniProt code: Q92882. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity. {ECO:0000269|PubMed:10092216}. |
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| Subunit: | |
Interacts with SRC and SMN1. Interacts with FASLG. {ECO:0000269|PubMed:10092216, ECO:0000269|PubMed:11551898, ECO:0000269|PubMed:19807924, ECO:0000269|Ref.5}. |
| Subcellular location: | |
Cytoplasm {ECO:0000305}. |
| Tissue specificity: | |
Ubiquitously expressed. Present in osteoclasts (at protein level). {ECO:0000269|PubMed:10092216}. |
| Domain: | |
The SH3 domain mediates interaction with SMN1. |
Annotations taken from UniProtKB at the EBI.