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PDBsum entry 3eft

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protein ligands metals links
Lyase PDB id
3eft
Jmol PyMol
Contents
Protein chain
256 a.a. *
Ligands
3BS
Metals
_ZN
_HG
Waters ×217
* Residue conservation analysis
PDB id:
3eft
Name: Lyase
Title: Crystal structure of the complex between carbonic anhydrase ii and a spin-labeled sulfonamide incorporating tempo moiety
Structure: Carbonic anhydrase 2. Chain: a. Synonym: carbonic anhydrase ii, ca-ii, carbonate dehydratase ii, carbonic anhydrasE C, cac. Engineered: yes
Source: Synthetic: yes. Other_details: chemically synthesized. This sequence occurs naturally in humans(homo sapiens).
Resolution:
1.85Å     R-factor:   0.195     R-free:   0.240
Authors: C.Temperini,A.Cecchi,A.Scozzafava,C.T.Supuran
Date:
10-Sep-08     Release date:   08-Sep-09    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P00918  (CAH2_HUMAN) -  Carbonic anhydrase 2
Seq:
Struc:
260 a.a.
256 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.4.2.1.1  - Carbonic anhydrase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: H2CO3 = CO2 + H2O
H(2)CO(3)
= CO(2)
+ H(2)O
      Cofactor: Zn(2+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     extracellular space   11 terms 
  Biological process     angiotensin-mediated signaling pathway   22 terms 
  Biochemical function     protein binding     6 terms  

 

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