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UniProt functional annotation for P32390 | ||
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| UniProt code: P32390. |
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| Organism: | |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. |
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| Function: | |
Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (By similarity). May be involved in cytokinesis. {ECO:0000250}. |
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| Subunit: | |
Component of the Arp2/3 complex composed of arp2, act2, arc1/p41-ARC, arc2/p34-ARC, arc3/p21-ARC, arc4/p20-ARC and arc5/p16- ARC. {ECO:0000269|PubMed:10588653}. |
| Subcellular location: | |
Cytoplasm, cytoskeleton, actin patch. |
| Similarity: | |
Belongs to the actin family. ARP3 subfamily. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.