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PDBsum entry 3dar
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Contents |
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* Residue conservation analysis
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PDB id:
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| Name: |
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Transferase
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Title:
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Crystal structure of d2 domain from human fgfr2
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Structure:
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Fibroblast growth factor receptor 2. Chain: a, b. Fragment: d2 domain, ig-like c2-type 2, unp residues 146-249. Synonym: fgfr-2, keratinocyte growth factor receptor 2, cd332 antigen. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: fgfr2, bek, kgfr, ksam. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Resolution:
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2.20Å
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R-factor:
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0.219
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R-free:
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0.255
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Authors:
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A.Brown,T.L.Blundell
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Key ref:
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A.Brown
and
t.l.blundell
Crystal structure of the fgfr2 d2 domain.
To be published,
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Date:
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30-May-08
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Release date:
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10-Jun-08
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PROCHECK
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Headers
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References
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P21802
(FGFR2_HUMAN) -
Fibroblast growth factor receptor 2 from Homo sapiens
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Seq:
Struc:
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821 a.a.
99 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.2.7.10.1
- receptor protein-tyrosine kinase.
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Reaction:
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L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H+
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L-tyrosyl-[protein]
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+
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ATP
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=
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O-phospho-L-tyrosyl-[protein]
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+
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ADP
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+
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H(+)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
