UniProt functional annotation for Q8N1Q1

UniProt code: Q8N1Q1.

Organism: Homo sapiens (Human).
Taxonomy: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
 
Function: Reversible hydration of carbon dioxide.
 
Catalytic activity: H(2)CO(3) = CO(2) + H(2)O.
Cofactor: Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250};
Enzyme regulation: Inhibited by acetazolamide. {ECO:0000269|PubMed:18618712}.
Biophysicochemical properties: Kinetic parameters: KM=13.8 mM for CO(2) {ECO:0000269|PubMed:18618712};
Tissue specificity: Expressed in thymus, small intestine, spleen, prostate, ovary, colon and testis. {ECO:0000269|PubMed:14600151}.
Similarity: Belongs to the alpha-carbonic anhydrase family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.