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PDBsum entry 3cyu

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Lyase PDB id
3cyu
Jmol
Contents
Protein chain
257 a.a.
Ligands
0CR
1CR
Metals
_XE ×2
_ZN
Waters ×185

References listed in PDB file
Key reference
Title Structure of a 129xe-Cryptophane biosensor complexed with human carbonic anhydrase ii.
Authors J.A.Aaron, J.M.Chambers, K.M.Jude, L.Di costanzo, I.J.Dmochowski, D.W.Christianson.
Ref. J Am Chem Soc, 2008, 130, 6942-6943.
PubMed id 18461940
Abstract
Cryptophanes represent an exciting class of xenon-encapsulating molecules that can be exploited as probes for nuclear magnetic resonance imaging. The 1.70 A resolution crystal structure of a cryptophane-derivatized benezenesulfonamide complexed with human carbonic anhydrase II shows how an encapsulated xenon atom can be directed to a specific biological target. The crystal structure confirms binding measurements indicating that the cryptophane cage does not strongly interact with the surface of the protein, which may enhance the sensitivity of 129Xe NMR spectroscopic measurements in solution.
PROCHECK
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 Headers