UniProt functional annotation for P08515

UniProt code: P08515.

Organism: Schistosoma japonicum (Blood fluke).
Taxonomy: Eukaryota; Metazoa; Platyhelminthes; Trematoda; Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
 
Function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
 
Function: GST isoenzymes appear to play a central role in the parasite detoxification system. Other functions are also suspected including a role in increasing the solubility of haematin in the parasite gut.
 
Catalytic activity: RX + glutathione = HX + R-S-glutathione.
Subunit: Homodimer.
Miscellaneous: There are at least two isoenzymes of GST in S.japonicum.
Similarity: Belongs to the GST superfamily. Mu family.
Similarity: Contains 1 GST C-terminal domain.
Similarity: Contains 1 GST N-terminal domain.

Annotations taken from UniProtKB at the EBI.