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PDBsum entry 3coi

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protein links
Transferase PDB id
3coi
Jmol PyMol
Contents
Protein chain
344 a.a. *
Waters ×175
* Residue conservation analysis
PDB id:
3coi
Name: Transferase
Title: Crystal structure of p38delta kinase
Structure: Mitogen-activated protein kinase 13. Chain: a. Synonym: stress-activated protein kinase 4, mitogen- activated protein kinase p38 delta, map kinase p38 delta. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Strain: hepg2. Gene: mapk13, prkm13, sapk4. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Resolution:
2.09Å     R-factor:   0.208     R-free:   0.242
Authors: S.Atwell,S.K.Burley,A.Houle,A.Ramos,J.M.Sauder,New York Sgx Research Center For Structural Genomics (Nysgxrc)
Key ref: S.Atwell et al. Crystal structure of p38delta kinase.. To be published, .
Date:
28-Mar-08     Release date:   15-Apr-08    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
O15264  (MK13_HUMAN) -  Mitogen-activated protein kinase 13
Seq:
Struc:
365 a.a.
344 a.a.*
Key:    PfamA domain  PfamB domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 3 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.2.7.11.24  - Mitogen-activated protein kinase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: ATP + a protein = ADP + a phosphoprotein
ATP
+ protein
= ADP
+ phosphoprotein
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytoplasm   3 terms 
  Biological process     intracellular signal transduction   14 terms 
  Biochemical function     nucleotide binding     8 terms  

 

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