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PDBsum entry 3caf

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protein links
Transferase PDB id
3caf

 

 

 

 

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Contents
Protein chain
100 a.a. *
Waters ×54
* Residue conservation analysis
PDB id:
3caf
Name: Transferase
Title: Crystal structure of hfgfr2 d2 domain
Structure: Fibroblast growth factor receptor 2. Chain: a. Fragment: ig-like c2-type 2. Synonym: fgfr-2, keratinocyte growth factor receptor 2, cd332 antigen. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fgfr2, bek, kgfr, ksam. Expressed in: escherichia coli. Expression_system_taxid: 562
Resolution:
1.96Å     R-factor:   0.191     R-free:   0.275
Authors: F.Guo,R.Dakshinamurthy,K.M.Kathir,S.K.K.Thallapuranam,J.Sakon
Key ref: F.Guo et al. Crystal structure analysis of the hfgfr2 d2 domain. To be published, .
Date:
19-Feb-08     Release date:   27-Jan-09    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P21802  (FGFR2_HUMAN) -  Fibroblast growth factor receptor 2 from Homo sapiens
Seq:
Struc:
 
Seq:
Struc:
821 a.a.
100 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.2.7.10.1  - receptor protein-tyrosine kinase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H+
L-tyrosyl-[protein]
+ ATP
= O-phospho-L-tyrosyl-[protein]
+ ADP
+ H(+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

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