|
|
||
|
|
|
|
|
UniProt functional annotation for Q805F7 | ||
|
|
|
|
|
|
||
| UniProt code: Q805F7. |
|
||
| Organism: | |
Agkistrodon contortrix contortrix (Southern copperhead). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Colubroidea; Viperidae; Crotalinae; Agkistrodon. |
|
||
|
||
| Function: | |
Inhibits fibrinogen interaction with platelets. Acts by binding to alpha-IIb/beta-3 (ITGA2B/ITGB3) on the platelet surface and inhibits ADP-induced platelet aggregation in human platelet-rich plasma. {ECO:0000269|PubMed:12450389}. |
|
||
| Subunit: | |
Heterodimer with subunit beta; disulfide-linked. {ECO:0000269|PubMed:12450389, ECO:0000269|PubMed:18391413}. |
| Subcellular location: | |
Secreted. |
| Tissue specificity: | |
Expressed by the venom gland. |
| Similarity: | |
Belongs to the disintegrin family. Dimeric disintegrin subfamily. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.