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UniProt functional annotation for Q8ML92 | ||
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| UniProt code: Q8ML92. |
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| Organism: | |
Drosophila melanogaster (Fruit fly). |
| Taxonomy: | |
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. |
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| Function: | |
Required for normal photoreceptor differentiation between Ras and Raf for EGFR signaling in the eye and for mitogen-activated protein kinase phosphorylation. Probably acts together with Cnk to promote Raf activation, perhaps by recruiting an activating kinase. {ECO:0000269|PubMed:16600911}. |
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| Subunit: | |
Interacts with the SAM domain of cnk. {ECO:0000269|PubMed:16600911}. |
| Subcellular location: | |
Cytoplasm {ECO:0000269|PubMed:16600911}. Membrane {ECO:0000269|PubMed:16600911}; Peripheral membrane protein {ECO:0000269|PubMed:16600911}. |
| Developmental stage: | |
Expressed ubiquitously throughout development. {ECO:0000269|PubMed:16600911}. |
| Miscellaneous: | |
'Aveugle' means 'blind' in French. |
Annotations taken from UniProtKB at the EBI.