PDBsum entry 3bpu

Transferase

PDB id: 3bpu

Contents

Protein chain

86 a.a. *

Metals

_ZN ×2

Waters ×74

* Residue conservation analysis

PDB id:

3bpu

Name:

Transferase

Title:

Crystal structure of the 3rd pdz domain of human membrane associated guanylate kinase, c677s and c709s double mutant

Structure:

Membrane-associated guanylate kinase, ww and pdz domain- containing protein 1. Chain: a. Fragment: 3rd pdz domain: residues 640-721. Synonym: bai1-associated protein 1, bap-1, membrane-associated guanylate kinase inverted 1, magi-1, atrophin-1-interacting protein 3, aip3, ww domain-containing protein 3, wwp3, trinucleotide repeat- containing gene 19 protein. Engineered: yes.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Tissue: brain. Gene: magi1, baiap1, bap1, tnrc19. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.60Å R-factor: 0.204 R-free: 0.251

Authors:

E.S.Pilka,V.Hozjan,C.Cooper,A.C.W.Pike,J.Elkins,D.A.Doyle,F.Von Delft,C.H.Arrowsmith,A.M.Edwards,J.Weigelt,U.Oppermann,Structural Genomics Consortium (Sgc)

Key ref:

E.S.Pilka et al. Crystal structure of the 3rd pdz domain of human membrane associated guanylate kinase, C677s and c709s double mutant.. To be published, .

Date:

19-Dec-07 Release date: 08-Jan-08

Protein chain

Q96QZ7  (MAGI1_HUMAN) -  Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 from Homo sapiens

Seq: 1491 a.a.

Struc: 86 a.a.*

* PDB and UniProt seqs differ at 8 residue positions (black crosses)