PDBsum entry 3bin

Cell adhesion

PDB id: 3bin

Contents

Protein chain

281 a.a. *

Ligands

GLY-THR-TYR-PHE-THR-HIS-GLU

Waters ×144

* Residue conservation analysis

PDB id:

3bin

Name:

Cell adhesion

Title:

Structure of the dal-1 and tslc1 (372-383) complex

Structure:

Band 4.1-like protein 3. Chain: a. Fragment: ferm domain. Synonym: 4.1b, differentially expressed in adenocarcinoma of the lung protein 1, dal-1. Engineered: yes. Cell adhesion molecule 1. Chain: b. Fragment: peptide from cytoplasmic domain, unp residues 400-411.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: epb41l3, dal1, kiaa0987. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: peptide synthetic

Resolution:

2.30Å R-factor: 0.181 R-free: 0.230

Authors:

R.D.Busam,C.H.Arrowsmith,R.Collins,L.G.Dahlgren,A.M.Edwards,S.Flodin, A.Flores,S.Graslund,M.Hammarstrom,A.Johansson,I.Johansson,A.Kallas, T.Karlberg,T.Kotenyova,L.Lehtio,M.Moche,M.E.Nilsson,P.Nordlund, T.Nyman,J.Sagemark,L.Svensson,A.G.Thorsell,L.Tresaugues,S.Van Den Berg,J.Weigelt,M.Welin,H.Berglund,C.Persson,B.M.Hallberg

Key ref:

R.D.Busam et al. (2011). Structural basis of tumor suppressor in lung cancer 1 (TSLC1) binding to differentially expressed in adenocarcinoma of the lung (DAL-1/4.1B). J Biol Chem, 286, 4511-4516. PubMed id: 21131357

Date:

30-Nov-07 Release date: 15-Jan-08

Protein chain

Q9Y2J2  (E41L3_HUMAN) -  Band 4.1-like protein 3 from Homo sapiens

Seq: 1087 a.a.

Struc: 281 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.?

J Biol Chem 286:4511-4516 (2011)

PubMed id: 21131357

Structural basis of tumor suppressor in lung cancer 1 (TSLC1) binding to differentially expressed in adenocarcinoma of the lung (DAL-1/4.1B).

R.D.Busam, A.G.Thorsell, A.Flores, M.Hammarström, C.Persson, B.Öbrink, B.M.Hallberg.

ABSTRACT

No abstract given.