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UniProt functional annotation for Q9KQW9 | ||
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| UniProt code: Q9KQW9. |
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| Organism: | |
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961). |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio. |
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| Function: | |
Involved in lipopolysaccharide (LPS) biosynthesis. Translocates lipid A-core from the inner to the outer leaflet of the inner membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity). Shows ATPase activity (PubMed:18024585). {ECO:0000255|HAMAP-Rule:MF_01703, ECO:0000269|PubMed:18024585}. |
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| Catalytic activity: | |
Reaction=ATP + H(2)O + lipid A-core oligosaccharide(Side 1) = ADP + phosphate + lipid A-core oligosaccharide(Side 2).; EC=7.5.2.6; Evidence={ECO:0000255|HAMAP-Rule:MF_01703}; |
| Subunit: | |
Homodimer. {ECO:0000255|HAMAP-Rule:MF_01703, ECO:0000269|PubMed:18024585}. |
| Subcellular location: | |
Cell inner membrane {ECO:0000255|HAMAP- Rule:MF_01703}; Multi-pass membrane protein {ECO:0000255|HAMAP- Rule:MF_01703}. |
| Domain: | |
In MsbA the ATP-binding domain (NBD) and the transmembrane domain (TMD) are fused. {ECO:0000255|HAMAP-Rule:MF_01703, ECO:0000269|PubMed:18024585}. |
| Similarity: | |
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family. {ECO:0000255|HAMAP-Rule:MF_01703}. |
Annotations taken from UniProtKB at the EBI.