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PDBsum entry 3auq

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Transcription PDB id
3auq
Jmol PyMol
Contents
Protein chain
253 a.a.
Ligands
CA9
Waters ×10
PDB id:
3auq
Name: Transcription
Title: Crystal structure of the human vitamin d receptor ligand bin domain complexed with yne-diene type analog of active 14-ep methyl-19-norvitamin d3
Structure: Vitamin d3 receptor. Chain: a. Fragment: ligand binding domain. Synonym: vdr, 1,25-dihydroxyvitamin d3 receptor, nuclear re subfamily 1 group i member 1. Engineered: yes. Mutation: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: vdr. Expressed in: escherichia coli. Expression_system_taxid: 562
Resolution:
2.64Å     R-factor:   0.237     R-free:   0.286
Authors: S.Kakuda,M.Takimoto-Kamimura
Key ref: D.Sawada et al. (2011). Development of 14-epi-19-nortachysterol and its unprecedented binding configuration for the human vitamin D receptor. J Am Chem Soc, 133, 7215-7221. PubMed id: 21500802 DOI: 10.1021/ja201481j
Date:
15-Feb-11     Release date:   14-Sep-11    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P11473  (VDR_HUMAN) -  Vitamin D3 receptor
Seq:
Struc:
427 a.a.
253 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     nucleus   1 term 
  Biological process     steroid hormone mediated signaling pathway   2 terms 
  Biochemical function     DNA binding     3 terms  

 

 
DOI no: 10.1021/ja201481j J Am Chem Soc 133:7215-7221 (2011)
PubMed id: 21500802  
 
 
Development of 14-epi-19-nortachysterol and its unprecedented binding configuration for the human vitamin D receptor.
D.Sawada, Y.Tsukuda, H.Saito, S.Kakuda, M.Takimoto-Kamimura, E.Ochiai, K.Takenouchi, A.Kittaka.
 
  ABSTRACT  
 
No abstract given.

 

 

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