PDBsum entry 3au4

Motor protein/apoptosis

PDB id: 3au4

Contents

Protein chains

524 a.a.

32 a.a.

Waters ×243

PDB id:

3au4

Name:

Motor protein/apoptosis

Title:

Structure of the human myosin-x myth4-ferm cassette bound to its specific cargo, dcc

Structure:

Myosin-x. Chain: a. Fragment: myth4-ferm cassette, unp residues 1486-2058. Synonym: unconventional myosin-10. Engineered: yes. Netrin receptor dcc. Chain: b. Fragment: p3 domain, unp residues 1390-1447. Synonym: colorectal cancer suppressor, immunoglobulin superfamily dcc

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: myo10, kiaa0799. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: dcc, igdcc1.

Resolution:

1.90Å R-factor: 0.215 R-free: 0.233

Authors:

Y.Hirano,T.Hatano,T.Hakoshima

Key ref:

Y.Hirano et al. (2011). Structural basis of cargo recognition by the myosin-X MyTH4-FERM domain. Embo J, 30, 2734-2747. PubMed id: 21642953

Date:

28-Jan-11 Release date: 13-Jul-11

Protein chain

Q9HD67  (MYO10_HUMAN) -  Unconventional myosin-X from Homo sapiens

Seq: 2058 a.a.

Struc: 524 a.a.*

Protein chain

P43146  (DCC_HUMAN) -  Netrin receptor DCC from Homo sapiens

Seq: 1447 a.a.

Struc: 32 a.a.

* PDB and UniProt seqs differ at 1 residue position (black cross)

Embo J 30:2734-2747 (2011)

PubMed id: 21642953

Structural basis of cargo recognition by the myosin-X MyTH4-FERM domain.

Y.Hirano, T.Hatano, A.Takahashi, M.Toriyama, N.Inagaki, T.Hakoshima.

ABSTRACT

No abstract given.