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PDBsum entry 3arf
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Immune system
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PDB id
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3arf
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Contents |
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293 a.a.
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99 a.a.
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203 a.a.
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235 a.a.
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PDB id:
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Immune system
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Title:
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Ternary crystal structure of the mouse nkt tcr-cd1d-c20:2
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Structure:
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Antigen-presenting glycoprotein cd1d1. Chain: a. Fragment: heavy chain. Engineered: yes. Beta-2-microglobulin. Chain: b. Engineered: yes. Nkt valpha14-jalpha18,nkt valpha14-jalpha18. Chain: c.
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Source:
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Mus musculus. Mouse. Organism_taxid: 10090. Gene: cd1d1, cd1.1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: b2m. Mus musculus, homo sapiens. Mouse, human.
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Resolution:
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2.90Å
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R-factor:
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0.227
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R-free:
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0.277
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Authors:
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K.S.Wun,J.Rossjohn
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Key ref:
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K.S.Wun
et al.
(2011).
A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells.
Immunity,
34,
327-339.
PubMed id:
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Date:
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27-Nov-10
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Release date:
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30-Mar-11
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PROCHECK
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Headers
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References
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P11609
(CD1D1_MOUSE) -
Antigen-presenting glycoprotein CD1d1 from Mus musculus
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Seq:
Struc:
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336 a.a.
293 a.a.*
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P01887
(B2MG_MOUSE) -
Beta-2-microglobulin from Mus musculus
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Seq:
Struc:
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119 a.a.
99 a.a.
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Immunity
34:327-339
(2011)
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PubMed id:
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A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells.
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K.S.Wun,
G.Cameron,
O.Patel,
S.S.Pang,
D.G.Pellicci,
L.C.Sullivan,
S.Keshipeddy,
M.H.Young,
A.P.Uldrich,
M.S.Thakur,
S.K.Richardson,
A.R.Howell,
P.A.Illarionov,
A.G.Brooks,
G.S.Besra,
J.McCluskey,
L.Gapin,
S.A.Porcelli,
D.I.Godfrey,
J.Rossjohn.
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ABSTRACT
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Literature references that cite this PDB file's key reference
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PubMed id
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Reference
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P.J.Brennan,
M.Brigl,
and
M.B.Brenner
(2013).
Invariant natural killer T cells: an innate activation scheme linked to diverse effector functions.
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Nat Rev Immunol,
13,
101-117.
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J.Rossjohn,
D.G.Pellicci,
O.Patel,
L.Gapin,
and
D.I.Godfrey
(2012).
Recognition of CD1d-restricted antigens by natural killer T cells.
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Nat Rev Immunol,
12,
845-857.
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E.J.Adams,
and
J.López-Sagaseta
(2011).
The immutable recognition of CD1d.
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Immunity,
34,
281-283.
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S.Aspeslagh,
Y.Li,
E.D.Yu,
N.Pauwels,
M.Trappeniers,
E.Girardi,
T.Decruy,
K.Van Beneden,
K.Venken,
M.Drennan,
L.Leybaert,
J.Wang,
R.W.Franck,
S.Van Calenbergh,
D.M.Zajonc,
and
D.Elewaut
(2011).
Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis.
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EMBO J,
30,
2294-2305.
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PDB codes:
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T.Mallevaey,
A.J.Clarke,
J.P.Scott-Browne,
M.H.Young,
L.C.Roisman,
D.G.Pellicci,
O.Patel,
J.P.Vivian,
J.L.Matsuda,
J.McCluskey,
D.I.Godfrey,
P.Marrack,
J.Rossjohn,
and
L.Gapin
(2011).
A molecular basis for NKT cell recognition of CD1d-self-antigen.
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Immunity,
34,
315-326.
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PDB codes:
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The most recent references are shown first.
Citation data come partly from CiteXplore and partly
from an automated harvesting procedure. Note that this is likely to be
only a partial list as not all journals are covered by
either method. However, we are continually building up the citation data
so more and more references will be included with time.
Where a reference describes a PDB structure, the PDB
codes are
shown on the right.
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