PDBsum entry 3agk

Translation

PDB id

3agk

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Contents

			Protein chain

					345 a.a. *

			Waters ×78

* Residue conservation analysis

PDB id:

3agk

Links

Name:

Translation

Title:

Crystal structure of archaeal translation termination factor, arf1

Structure:

Peptide chain release factor subunit 1. Chain: a. Synonym: translation termination factor arf1. Engineered: yes

Source:

Aeropyrum pernix. Organism_taxid: 56636. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

2.10Å

R-factor:

0.213

R-free:

0.260

Authors:

K.Kobayashi,I.Kikuno,R.Ishitani,K.Ito,O.Nureki

Key ref:

K.Saito et al. (2010). Omnipotent role of archaeal elongation factor 1 alpha (EF1α in translational elongation and termination, and quality control of protein synthesis. Proc Natl Acad Sci U S A, 107, 19242-19247. PubMed id: 20974926

Date:

01-Apr-10

Release date:

03-Nov-10

PROCHECK

	Headers

	References

Protein chain

Q9YAF1 (RF1_AERPE) - Peptide chain release factor subunit 1 from Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)

Seq: Struc:					373 a.a. 345 a.a.

Key:

PfamA domain

Secondary structure

CATH domain

	Proc Natl Acad Sci U S A 107:19242-19247 (2010)
PubMed id: 20974926

Omnipotent role of archaeal elongation factor 1 alpha (EF1α in translational elongation and termination, and quality control of protein synthesis.
K.Saito, K.Kobayashi, M.Wada, I.Kikuno, A.Takusagawa, M.Mochizuki, T.Uchiumi, R.Ishitani, O.Nureki, K.Ito.

ABSTRACT

No abstract given.

Literature references that cite this PDB file's key reference

PubMed id

Reference

23072885

M.Graille, and B.Séraphin (2012).
Surveillance pathways rescuing eukaryotic ribosomes lost in translation.

Nat Rev Mol Cell Biol, 13, 727-735.

21292982

D.Barthelme, S.Dinkelaker, S.V.Albers, P.Londei, U.Ermler, and R.Tampé (2011).
Ribosome recycling depends on a mechanistic link between the FeS cluster domain and a conformational switch of the twin-ATPase ABCE1.

Proc Natl Acad Sci U S A, 108, 3228-3233.

21448132

V.P.Pisareva, M.A.Skabkin, C.U.Hellen, T.V.Pestova, and A.V.Pisarev (2011).
Dissociation by Pelota, Hbs1 and ABCE1 of mammalian vacant 80S ribosomes and stalled elongation complexes.

EMBO J, 30, 1804-1817.

The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time.