PDBsum entry 3aaj

Apoptosis

PDB id: 3aaj

Contents

Protein chain

167 a.a. *

Metals

_CA ×6

Waters ×58

* Residue conservation analysis

PDB id:

3aaj

Name:

Apoptosis

Title:

Crystal structure of ca2+-bound form of des3-23alg-2deltagf122

Structure:

Programmed cell death protein 6. Chain: a, b. Fragment: residues 2-191. Synonym: calcium-binding protein alg-2, apoptosis-linked gene 2 protein. Engineered: yes. Mutation: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

2.40Å R-factor: 0.200 R-free: 0.266

Authors:

H.Suzuki,T.Inuzuka,M.Kawasaki,H.Shibata,S.Wakatsuki,M.Maki

Key ref:

T.Inuzuka et al. (2010). Molecular basis for defect in Alix-binding by alternatively spliced isoform of ALG-2 (ALG-2DeltaGF122) and structural roles of F122 in target recognition. Bmc Struct Biol, 10, 25-25. PubMed id: 20691033

Date:

19-Nov-09 Release date: 08-Sep-10

Protein chains

O75340  (PDCD6_HUMAN) -  Programmed cell death protein 6 from Homo sapiens

Seq: 191 a.a.

Struc: 167 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Bmc Struct Biol 10:25-25 (2010)

PubMed id: 20691033

Molecular basis for defect in Alix-binding by alternatively spliced isoform of ALG-2 (ALG-2DeltaGF122) and structural roles of F122 in target recognition.

T.Inuzuka, H.Suzuki, M.Kawasaki, H.Shibata, S.Wakatsuki, M.Maki.

ABSTRACT

No abstract given.