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PDBsum entry 3v19

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protein ligands metals Protein-protein interface(s) links
Hormone PDB id
3v19
Jmol
Contents
Protein chains
21 a.a.
30 a.a.
Ligands
IPH
Metals
_CL ×2
_ZN ×2
Waters ×66
PDB id:
3v19
Name: Hormone
Title: Forestalling insulin fibrillation by insertion of a chiral c mechanism-based application of protein engineering to globa
Structure: Insulin. Chain: a, c. Engineered: yes. Insulin. Chain: b, d. Engineered: yes
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Organism_taxid: 9606
Resolution:
2.00Å     R-factor:   0.208     R-free:   0.266
Authors: Z.L.Wan,Q.X.Hua,N.P.Wickramasinghe,K.Huang,A.T.Petkova,S.Q.H N.B.Phillips,I.J.Yeh,J.Whittake,F.Ismail-Beigi,P.G.Katsoyya R.Tycko,M.A.Weiss
Key ref: Z.L.Wan et al. Forestalling insulin fibrillation by insertion of a c clamp mechanism-Based application of protein engineer global health. To be published, .
Date:
09-Dec-11     Release date:   12-Dec-12    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P01308  (INS_HUMAN) -  Insulin
Seq:
Struc:
110 a.a.
21 a.a.*
Protein chains
Pfam   ArchSchema ?
P01308  (INS_HUMAN) -  Insulin
Seq:
Struc:
110 a.a.
30 a.a.
Key:    PfamA domain  Secondary structure
* PDB and UniProt seqs differ at 3 residue positions (black crosses)

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     extracellular region   1 term 
  Biochemical function     hormone activity     1 term