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PDBsum entry 3umh

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protein ligands metals links
Metal binding protein PDB id
3umh
Jmol
Contents
Protein chain
180 a.a.
Ligands
ACT ×2
Metals
_CD ×9
Waters ×95
PDB id:
3umh
Name: Metal binding protein
Title: X-ray structure of the e2 domain of the human amyloid precur protein (app) in complex with cadmium
Structure: Amyloid beta a4 protein. Chain: a. Fragment: human amyloid precursor protein e2 domain. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.00Å     R-factor:   0.198     R-free:   0.240
Authors: S.O.Dahms,I.Konnig,D.Roeser,K.H.Guhrs,M.E.Than
Key ref: S.O.Dahms et al. (2012). Metal binding dictates conformation and function of the amyloid precursor protein (APP) E2 domain. J Mol Biol, 416, 438-452. PubMed id: 22245578
Date:
13-Nov-11     Release date:   25-Jan-12    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P05067  (A4_HUMAN) -  Amyloid beta A4 protein
Seq:
Struc:
 
Seq:
Struc:
770 a.a.
180 a.a.
Key:    PfamA domain  PfamB domain  Secondary structure  CATH domain

 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     nervous system development   1 term 

 

 
J Mol Biol 416:438-452 (2012)
PubMed id: 22245578  
 
 
Metal binding dictates conformation and function of the amyloid precursor protein (APP) E2 domain.
S.O.Dahms, I.Könnig, D.Roeser, K.H.Gührs, M.C.Mayer, D.Kaden, G.Multhaup, M.E.Than.
 
  ABSTRACT  
 
No abstract given.