spacer
spacer

PDBsum entry 3u4n

Go to PDB code: 
protein Protein-protein interface(s) links
Hormone PDB id
3u4n
Jmol
Contents
Protein chains
21 a.a.
29 a.a.
Waters ×84
PDB id:
3u4n
Name: Hormone
Title: A novel covalently linked insulin dimer
Structure: Insulin a chain. Chain: a. Engineered: yes. Insulin b chain. Chain: b. Engineered: yes. Mutation: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ins. Gene: ins
Resolution:
1.98Å     R-factor:   0.170     R-free:   0.217
Authors: M.Norrman,T.N.Vinther
Key ref: T.N.Vinther et al. (2012). Novel covalently linked insulin dimer engineered to investigate the function of insulin dimerization. PLoS One, 7, e30882. PubMed id: 22363506 DOI: 10.1371/journal.pone.0030882
Date:
10-Oct-11     Release date:   11-Apr-12    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P01308  (INS_HUMAN) -  Insulin
Seq:
Struc:
110 a.a.
21 a.a.
Protein chain
Pfam   ArchSchema ?
P01308  (INS_HUMAN) -  Insulin
Seq:
Struc:
110 a.a.
29 a.a.*
Key:    PfamA domain  Secondary structure
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     extracellular region   1 term 
  Biochemical function     hormone activity     1 term  

 

 
DOI no: 10.1371/journal.pone.0030882 PLoS One 7:e30882 (2012)
PubMed id: 22363506  
 
 
Novel covalently linked insulin dimer engineered to investigate the function of insulin dimerization.
T.N.Vinther, M.Norrman, H.M.Strauss, K.Huus, M.Schlein, T...Pedersen, T.Kjeldsen, K.J.Jensen, F.Hubálek.
 
  ABSTRACT  
 
No abstract given.