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PDBsum entry 3qrd

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protein ligands Protein-protein interface(s) links
Hydrolase inhibitor PDB id
3qrd
Jmol
Contents
Protein chains
111 a.a.
104 a.a.
Ligands
PEG ×6
Waters ×108
PDB id:
3qrd
Name: Hydrolase inhibitor
Title: Crystal structure of l68v mutant of human cystatin c
Structure: Cystatin-c. Chain: a, b, c, d. Synonym: cystatin-3, gamma-trace, neuroendocrine basic poly post-gamma-globulin. Engineered: yes. Mutation: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cst3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.19Å     R-factor:   0.218     R-free:   0.293
Authors: M.Orlikowska,D.Borek,Z.Otwinowski,P.Skowron,A.Szymanska
Key ref: M.Orlikowska et al. Crystal structure of l68V mutant of human cystatin c. To be published, .
Date:
17-Feb-11     Release date:   29-Feb-12    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P01034  (CYTC_HUMAN) -  Cystatin-C
Seq:
Struc:
146 a.a.
111 a.a.*
Protein chain
Pfam   ArchSchema ?
P01034  (CYTC_HUMAN) -  Cystatin-C
Seq:
Struc:
146 a.a.
104 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 2 residue positions (black crosses)

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     extracellular region   3 terms 
  Biological process     defense response   11 terms 
  Biochemical function     protein binding     6 terms