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PDBsum entry 3qk2

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protein ligands links
DNA binding protein PDB id
3qk2
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Contents
Protein chain
132 a.a. *
Ligands
SCN
Waters ×129
* Residue conservation analysis
PDB id:
3qk2
Name: DNA binding protein
Title: Structure-based analysis of the interaction between the simi 40 t-antigen origin binding domain and single-stranded DNA
Structure: Large t antigen. Chain: a. Fragment: origin binding domain. Synonym: lt, lt-ag. Engineered: yes
Source: Simian virus 40. Sv40. Organism_taxid: 10633. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
1.64Å     R-factor:   0.165     R-free:   0.187
Authors: G.Meinke,P.A.Bullock,A.Bohm
Key ref: G.Meinke et al. (2011). Structure-based analysis of the interaction between the simian virus 40 T-antigen origin binding domain and single-stranded DNA. J Virol, 85, 818-827. PubMed id: 20980496 DOI: 10.1128/JVI.01738-10
Date:
31-Jan-11     Release date:   23-Feb-11    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P03070  (LT_SV40) -  Large T antigen
Seq:
Struc:
 
Seq:
Struc:
708 a.a.
132 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 4 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.3.6.4.-  - ?????
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     DNA replication   1 term 
  Biochemical function     DNA replication origin binding     1 term  

 

 
DOI no: 10.1128/JVI.01738-10 J Virol 85:818-827 (2011)
PubMed id: 20980496  
 
 
Structure-based analysis of the interaction between the simian virus 40 T-antigen origin binding domain and single-stranded DNA.
G.Meinke, P.J.Phelan, A.Fradet-Turcotte, A.Bohm, J.Archambault, P.A.Bullock.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
21636896 G.Meinke, P.Phelan, A.Fradet-Turcotte, J.Archambault, and P.A.Bullock (2011).
Structure-based design of a disulfide-linked oligomeric form of the simian virus 40 (SV40) large T antigen DNA-binding domain.
  Acta Crystallogr D Biol Crystallogr, 67, 560-567.
PDB code: 3qn2
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time. Where a reference describes a PDB structure, the PDB code is shown on the right.

 

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