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PDBsum entry 3q6e

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protein ligands Protein-protein interface(s) links
Hormone PDB id
3q6e
Jmol
Contents
Protein chains
21 a.a.
29 a.a.
30 a.a.
Ligands
QQ7
Waters ×59
PDB id:
3q6e
Name: Hormone
Title: Human insulin in complex with cucurbit[7]uril
Structure: Insulin a chain. Chain: a, c. Fragment: unp residues 90-110. Engineered: yes. Insulin b chain. Chain: b, d. Fragment: unp residues 25-54. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ins. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Expression_system_taxid: 4932
Resolution:
2.05Å     R-factor:   0.211     R-free:   0.253
Authors: J.M.Chinai,A.B.Taylor,N.D.Hargreaves,L.M.Ryno,C.A.Morris,P.J A.R.Urbach
Key ref: J.M.Chinai et al. (2011). Molecular recognition of insulin by a synthetic receptor. J Am Chem Soc, 133, 8810-8813. PubMed id: 21473587
Date:
31-Dec-10     Release date:   20-Apr-11    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P01308  (INS_HUMAN) -  Insulin
Seq:
Struc:
110 a.a.
21 a.a.
Protein chain
Pfam   ArchSchema ?
P01308  (INS_HUMAN) -  Insulin
Seq:
Struc:
110 a.a.
29 a.a.
Protein chain
Pfam   ArchSchema ?
P01308  (INS_HUMAN) -  Insulin
Seq:
Struc:
110 a.a.
30 a.a.
Key:    PfamA domain  Secondary structure

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     extracellular region   1 term 
  Biochemical function     hormone activity     1 term  

 

 
J Am Chem Soc 133:8810-8813 (2011)
PubMed id: 21473587  
 
 
Molecular recognition of insulin by a synthetic receptor.
J.M.Chinai, A.B.Taylor, L.M.Ryno, N.D.Hargreaves, C.A.Morris, P.J.Hart, A.R.Urbach.
 
  ABSTRACT  
 
No abstract given.