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PDBsum entry 3q27

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protein ligands links
Sugar binding protein, protein fibril PDB id
3q27
Jmol
Contents
Protein chain
390 a.a.
Ligands
MAL
SO4 ×3
GOL
Waters ×471
PDB id:
3q27
Name: Sugar binding protein, protein fibril
Title: Cyrstal structure of human alpha-synuclein (32-57) fused to binding protein (mbp)
Structure: Maltose-binding periplasmic protein/alpha-synucle chimeric protein. Chain: a. Engineered: yes
Source: Escherichia coli, homo sapiens. Organism_taxid: 562, 9606. Gene: snca. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
1.30Å     R-factor:   0.132     R-free:   0.156
Authors: M.Zhao,M.R.Sawaya,D.Cascio,D.Eisenberg
Key ref: M.Zhao et al. (2011). Structures of segments of α-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation. Protein Sci, 20, 996-1004. PubMed id: 21462277 DOI: 10.1002/pro.630
Date:
19-Dec-10     Release date:   01-Jun-11    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P0AEX9  (MALE_ECOLI) -  Maltose-binding periplasmic protein
Seq:
Struc:
396 a.a.
390 a.a.*
Protein chain
Pfam   ArchSchema ?
P37840  (SYUA_HUMAN) -  Alpha-synuclein
Seq:
Struc:
140 a.a.
390 a.a.*
Key:    PfamA domain  PfamB domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 34 residue positions (black crosses)

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     periplasmic space   5 terms 
  Biological process     transport   7 terms 
  Biochemical function     transporter activity     4 terms  

 

 
DOI no: 10.1002/pro.630 Protein Sci 20:996-1004 (2011)
PubMed id: 21462277  
 
 
Structures of segments of α-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation.
M.Zhao, D.Cascio, M.R.Sawaya, D.Eisenberg.
 
  ABSTRACT  
 
No abstract given.