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PDBsum entry 3pxa

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protein ligands metals links
Protein binding PDB id
3pxa
Jmol
Contents
Protein chain
207 a.a.
Ligands
SO4
Metals
_NI
Waters ×29
PDB id:
3pxa
Name: Protein binding
Title: Impact of brca1 brct domain missense substitutions on phosph recognition: g1656d
Structure: Breast cancer type 1 susceptibility protein. Chain: a. Fragment: brct domain, unp residues 1646-1859. Synonym: ring finger protein 53. Engineered: yes. Mutation: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brca1, rnf53. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Resolution:
2.55Å     R-factor:   0.239     R-free:   0.261
Authors: N.Coquelle,R.Green,J.N.M.Glover
Key ref: N.Coquelle et al. (2011). Impact of BRCA1 BRCT domain missense substitutions on phosphopeptide recognition. Biochemistry, 50, 4579-4589. PubMed id: 21473589 DOI: 10.1021/bi2003795
Date:
09-Dec-10     Release date:   20-Apr-11    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P38398  (BRCA1_HUMAN) -  Breast cancer type 1 susceptibility protein
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
1863 a.a.
207 a.a.*
Key:    PfamA domain  PfamB domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     nucleus   1 term 
  Biological process     DNA repair   1 term 
  Biochemical function     DNA binding     3 terms  

 

 
DOI no: 10.1021/bi2003795 Biochemistry 50:4579-4589 (2011)
PubMed id: 21473589  
 
 
Impact of BRCA1 BRCT domain missense substitutions on phosphopeptide recognition.
N.Coquelle, R.Green, J.N.Glover.
 
  ABSTRACT  
 
No abstract given.