PDBsum entry 3ptl

Hydrolase/inhibitor

PDB id: 3ptl

Contents

Protein chain

279 a.a. *

Ligands

LYS-GLY-GLU-ALA-ASP-ALA-LEU-SER-LEU-ASP

Waters ×438

* Residue conservation analysis

PDB id:

3ptl

Name:

Hydrolase/inhibitor

Title:

Crystal structure of proteinase k inhibited by a lactoferrin nonapeptide, lys-gly-glu-ala-asp-ala-leu-ser-leu-asp at 1.3 a resolution.

Structure:

Proteinase k. Chain: a. Synonym: endopeptidase k, tritirachium alkaline proteinase. 10-mer peptide from lactoferrin. Chain: b. Engineered: yes

Source:

Engyodontium album. Organism_taxid: 37998. Synthetic: yes. Other_details: synthetic construct

Resolution:

1.30Å R-factor: 0.202 R-free: 0.250

Authors:

P.K.Shukla,M.Sinha,P.Kaur,S.Sharma,T.P.Singh

Key ref:

P.K.Shukla et al. Crystal structure of proteinase k inhibited by a lact nonapeptide, Lys-Gly-Glu-Ala-Asp-Ala-Leu-Ser-Leu-Asp a resolution.. To be published, .

Date:

03-Dec-10 Release date: 22-Dec-10

Protein chain

P06873  (PRTK_PARAQ) -  Proteinase K from Parengyodontium album

Seq: 384 a.a.

Struc: 279 a.a.

Enzyme reactions

• Enzyme class: E.C.3.4.21.64 - peptidase K.
• Reaction: Hydrolysis of keratin and of other proteins, with subtilisin-like specificity. Hydrolyzes peptides amides.