spacer
spacer

PDBsum entry 3p2x

Go to PDB code: 
protein ligands metals Protein-protein interface(s) links
Hormone PDB id
3p2x
Jmol
Contents
Protein chains
21 a.a.
30 a.a.
Ligands
IPH
Metals
_CL ×2
_ZN ×2
Waters ×59
PDB id:
3p2x
Name: Hormone
Title: Insulin fibrillation is the janus face of induced fit. A chi stabilizes the native state at the expense of activity
Structure: Insulin. Chain: a, c. Fragment: unp residues 90-110. Synonym: insulin a chain. Engineered: yes. Insulin. Chain: b, d. Fragment: unp residues 25-54. Synonym: insulin b chain.
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Organism_taxid: 9606
Resolution:
2.00Å     R-factor:   0.229     R-free:   0.314
Authors: Q.X.Hua,Z.L.Wan,K.Huang,S.Q.Hu,N.F.Phillip,W.H.Jia,J.Whittin G.G.Dodson,P.G.Katsoyannis,M.A.Weiss
Key ref: Q.X.Hua et al. Insulin fibrillation is the janus face of induced fit chiral clamp stabilizes the native state at the expen activity. To be published, .
Date:
04-Oct-10     Release date:   23-Nov-11    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
P01308  (INS_HUMAN) -  Insulin
Seq:
Struc:
110 a.a.
21 a.a.
Protein chains
Pfam   ArchSchema ?
P01308  (INS_HUMAN) -  Insulin
Seq:
Struc:
110 a.a.
30 a.a.*
Key:    PfamA domain  Secondary structure
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     extracellular region   1 term 
  Biochemical function     hormone activity     1 term