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PDBsum entry 3o2d

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protein Protein-protein interface(s) links
Immune system PDB id
3o2d
Jmol
Contents
Protein chains
216 a.a. *
222 a.a. *
178 a.a. *
Waters ×215
* Residue conservation analysis
PDB id:
3o2d
Name: Immune system
Title: Crystal structure of HIV-1 primary receptor cd4 in complex w potent antiviral antibody
Structure: Ibalizumab light chain. Chain: l. Engineered: yes. Ibalizumab heavy chain. Chain: h. Engineered: yes. T-cell surface glycoprotein cd4. Chain: a. Fragment: unp residues 26-207.
Source: Mus musculus. Mouse. Organism_taxid: 10090. Expressed in: mus musculus. Expression_system_taxid: 10090. Expression_system_cell_line: ns/o. Homo sapiens. Human. Organism_taxid: 9606.
Resolution:
2.19Å     R-factor:   0.194     R-free:   0.224
Authors: M.M.Freeman,M.S.Seaman,S.Rits-Volloch,X.Hong,D.D.Ho,B.Chen
Key ref: M.M.Freeman et al. (2010). Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody. Structure, 18, 1632-1641. PubMed id: 21134642
Date:
22-Jul-10     Release date:   22-Dec-10    
PROCHECK
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 Headers
 References

Protein chain
No UniProt id for this chain
Struc: 216 a.a.
Protein chain
No UniProt id for this chain
Struc: 222 a.a.
Protein chain
Pfam   ArchSchema ?
P01730  (CD4_HUMAN) -  T-cell surface glycoprotein CD4
Seq:
Struc:
458 a.a.
178 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     integral to membrane   1 term 
  Biological process     cell adhesion   1 term 

 

 
Structure 18:1632-1641 (2010)
PubMed id: 21134642  
 
 
Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody.
M.M.Freeman, M.S.Seaman, S.Rits-Volloch, X.Hong, C.Y.Kao, D.D.Ho, B.Chen.
 
  ABSTRACT  
 
No abstract given.