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PDBsum entry 3lx3

Go to PDB code: 
protein ligands metals links
Biosynthetic protein PDB id
3lx3
Jmol PyMol
Contents
Protein chain
163 a.a. *
Ligands
XTN
Metals
_ZN
Waters ×177
* Residue conservation analysis
PDB id:
3lx3
Name: Biosynthetic protein
Title: Plasmodium vivax 6-pyruvoyltetrahydropterin synthase (ptps) in complex with xanthopterin
Structure: 6-pyruvoyl tetrahydrobiopterin synthase. Chain: a. Engineered: yes
Source: Plasmodium vivax. Organism_taxid: 5855. Gene: pvx_114505. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
1.55Å     R-factor:   0.150     R-free:   0.167
Authors: E.T.Larson,E.A.Merritt,Medical Structural Genomics Of Pathogenic Protozoa (Msgpp)
Key ref: E.T.Larson et al. Structural analysis of the dual-Functional 6-Pyruvoyltetrahydropterin synthase from malaria parasites.. To be published, .
Date:
24-Feb-10     Release date:   09-Mar-10    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
A5K2B2  (A5K2B2_PLAVS) -  Putative 6-pyruvoyl tetrahydrobiopterin synthase, putative
Seq:
Struc:
172 a.a.
163 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.4.2.3.12  - 6-pyruvoyltetrahydropterin synthase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
Biopterin Biosynthesis
      Reaction: 7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8- tetrahydropterin + triphosphate
7,8-dihydroneopterin 3'-triphosphate
= 6-pyruvoyl-5,6,7,8- tetrahydropterin
+ triphosphate
      Cofactor: Mg(2+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biochemical function     metal ion binding     1 term  

 

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