spacer
spacer

PDBsum entry 3l73
Go to PDB code: 
protein ligands Protein-protein interface(s) links
Oxidoreductase PDB id
3l73

 

 

 

 

Loading ...

 
JSmol PyMol  
Contents
Protein chains
444 a.a. *
420 a.a. *
380 a.a. *
241 a.a. *
196 a.a. *
101 a.a. *
80 a.a. *
70 a.a. *
46 a.a. *
61 a.a. *
43 a.a. *
Ligands
PEE ×6
HEM ×4
JZZ ×2
_UQ ×2
GOL ×2
HEC ×2
CDL ×4
BOG ×5
FES ×2
Waters ×19
* Residue conservation analysis
PDB id:
3l73
Name: Oxidoreductase
Title: Cytochrome bc1 complex from chicken with triazolone inhibitor
Structure: Mitochondrial ubiquinol-cytochromE-C reductase complex core protein i. Chain: a, n. Mitochondrial ubiquinol-cytochromE-C reductase complex core protein 2. Chain: b, o. Cytochrome b. Chain: c, p. Synonym: ubiquinol-cytochromE-C reductase complex cytochrome b
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Organism_taxid: 9031
Resolution:
3.04Å     R-factor:   0.259     R-free:   0.293
Authors: L.Huang,E.A.Berry
Key ref: L.Huang and e.a.berry Famoxadone and related inhibitors bind like methoxy acrylate inhibitors in the qo site of the bc1 compl and fix the rieske iron-Sulfur protein in a positio close to but distinct from that seen with stigmatellin and other "distal" qo inhibitors.. To be published, .
Date:
27-Dec-09     Release date:   02-Feb-10    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
D0VX31  (D0VX31_CHICK) -  Mitochondrial ubiquinol-cytochrome-c reductase complex core protein i from Gallus gallus
Seq:
Struc: 		446 a.a.
444 a.a.
Protein chains
Pfam   ArchSchema ?
D0VX29  (D0VX29_CHICK) -  Mitochondrial ubiquinol-cytochrome-c reductase complex core protein 2 from Gallus gallus
Seq:
Struc: 		441 a.a.
420 a.a.
Protein chains
Pfam   ArchSchema ?
P18946  (CYB_CHICK) -  Cytochrome b from Gallus gallus
Seq:
Struc: 		380 a.a.
380 a.a.
Protein chains
Pfam   ArchSchema ?
D0VX26  (D0VX26_CHICK) -  Cytochrome c from Gallus gallus
Seq:
Struc: 		241 a.a.
241 a.a.
Protein chains
Pfam   ArchSchema ?
Q5ZLR5  (UCRI_CHICK) -  Cytochrome b-c1 complex subunit Rieske, mitochondrial from Gallus gallus
Seq:
Struc: 		272 a.a.
196 a.a.
Protein chains
Pfam   ArchSchema ?
D0VX30  (D0VX30_CHICK) -  Cytochrome b-c1 complex subunit 7 from Gallus gallus
Seq:
Struc: 		110 a.a.
101 a.a.
Protein chains
Pfam   ArchSchema ?
D0VX32  (D0VX32_CHICK) -  Cytochrome b-c1 complex subunit 8 from Gallus gallus
Seq:
Struc: 		81 a.a.
80 a.a.
Protein chains
Pfam   ArchSchema ?
D0VX28  (D0VX28_CHICK) -  Cytochrome b-c1 complex subunit 6 from Gallus gallus
Seq:
Struc: 		77 a.a.
70 a.a.
Protein chain
Pfam   ArchSchema ?
Q5ZLR5  (UCRI_CHICK) -  Cytochrome b-c1 complex subunit Rieske, mitochondrial from Gallus gallus
Seq:
Struc: 		272 a.a.
46 a.a.*
Protein chains
Pfam   ArchSchema ?
D0VX27  (D0VX27_CHICK) -  Complex III subunit 9 from Gallus gallus
Seq:
Struc: 		61 a.a.
61 a.a.
Protein chain
Pfam   ArchSchema ?
Q5ZLR5  (UCRI_CHICK) -  Cytochrome b-c1 complex subunit Rieske, mitochondrial from Gallus gallus
Seq:
Struc: 		272 a.a.
43 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 27 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: Chains E, I, R, V: E.C.7.1.1.8  - quinol--cytochrome-c reductase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)- [cytochrome c](out) + 2 H(+)(out)
quinol
 + 2 × Fe(III)-[cytochrome c](out)
 =
quinone
Bound ligand (Het Group name = UQ)
matches with 42.11% similarity 		+ 2 × Fe(II)- [cytochrome c](out)
 + 2 × H(+)(out)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

spacer
spacer