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PDBsum entry 3itr

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protein links
Interleukin-13 PDB id
3itr
Jmol
Contents
Protein chain
109 a.a.
Theoretical model
PDB id:
3itr
Name: Interleukin-13
Structure: Interleukin-13 model 1 (theoretical model)
Source: Human (homo sapiens)
Authors: P.Bamborough,D.Duncan,W.G.Richards
Key ref: P.Bamborough et al. (1994). Predictive modelling of the 3-D structure of interleukin-13. Protein Eng, 7, 1077-1082. PubMed id: 7530359
Date:
06-Sep-94     Release date:   20-Dec-94    
PROCHECK
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 Headers
 References

Protein chain
No UniProt id for this chain
Struc: 109 a.a.
Key:    Secondary structure

 

 
Protein Eng 7:1077-1082 (1994)
PubMed id: 7530359  
 
 
Predictive modelling of the 3-D structure of interleukin-13.
P.Bamborough, D.Duncan, W.G.Richards.
 
  ABSTRACT  
 
Several atomic structures are now available for the family of helical cytokines, which includes growth hormone as well as many of the interleukins. Using structural information from five members of this family, two alternative models of interleukin (IL)-13 are proposed. IL-13 has biological properties similar to those of IL-4 and, like the other interleukins, is a potentially important pharmaceutical target. The model of IL-13 is discussed and compared with the known interleukin structures.
 

Literature references that cite this PDB file's key reference

  PubMed id Reference
16957991 J.Ruan, K.Chen, J.A.Tuszynski, and L.A.Kurgan (2006).
Quantitative analysis of the conservation of the tertiary structure of protein segments.
  Protein J, 25, 301-315.  
  15626157 S.Avery, L.Rothwell, W.D.Degen, V.E.Schijns, J.Young, J.Kaufman, and P.Kaiser (2004).
Characterization of the first nonmammalian T2 cytokine gene cluster: the cluster contains functional single-copy genes for IL-3, IL-4, IL-13, and GM-CSF, a gene for IL-5 that appears to be a pseudogene, and a gene encoding another cytokinelike transcript, KK34.
  J Interferon Cytokine Res, 24, 600-610.  
11488979 J.Zuegg, D.C.Webb, P.S.Foster, and M.G.Casarotto (2001).
Structural model of human IL-13 defines the spatial interactions with the IL-13Ralpha/IL-4Ralpha receptor.
  Immunol Cell Biol, 79, 332-339.
PDB code: 1j9u
11418305 K.T.Nash, J.P.Thompson, and W.Debinski (2001).
Molecular targeting of malignant gliomas with novel multiply-mutated interleukin 13-based cytotoxins.
  Crit Rev Oncol Hematol, 39, 87-98.  
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time. Where a reference describes a PDB structure, the PDB code is shown on the right.