UniProt functional annotation for P38383

UniProt code: P38383.

Organism: Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8).
Taxonomy: Bacteria; Deinococcus-Thermus; Deinococci; Thermales; Thermaceae; Thermus.
 
Function: Essential subunit of the protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
 
Subunit: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with SecDF, and other proteins may be involved. The channel interacts with SecA via subunit SecY. {ECO:0000269|PubMed:18923527}.
Subcellular location: Cell inner membrane {ECO:0000255|HAMAP- Rule:MF_00422, ECO:0000269|PubMed:18923527}; Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00422, ECO:0000269|PubMed:18923527}.
Similarity: Belongs to the SecE/SEC61-gamma family. {ECO:0000255|HAMAP- Rule:MF_00422}.
Sequence caution: Sequence=L10348; Type=Frameshift; Evidence={ECO:0000305};

Annotations taken from UniProtKB at the EBI.