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UniProt functional annotation for O74101 | ||
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| UniProt code: O74101. |
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| Organism: | |
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3). |
| Taxonomy: | |
Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus. |
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| Function: | |
Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes. {ECO:0000255|HAMAP-Rule:MF_01122}. |
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| Subunit: | |
Homotetramer. {ECO:0000255|HAMAP-Rule:MF_01122}. |
| Subcellular location: | |
Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01122}. Chromosome {ECO:0000255|HAMAP-Rule:MF_01122}. |
| Ptm: | |
Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity. {ECO:0000255|HAMAP-Rule:MF_01122}. |
| Similarity: | |
Belongs to the histone-like Alba family. {ECO:0000255|HAMAP-Rule:MF_01122}. |
Annotations taken from UniProtKB at the EBI.