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PDBsum entry 2yyn
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Transcription
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PDB id
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2yyn
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Contents |
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* Residue conservation analysis
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PDB id:
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Transcription
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Title:
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Crystal structure of human bromodomain protein
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Structure:
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Transcription intermediary factor 1-alpha. Chain: a, b, c, d. Fragment: bromo domain. Synonym: tif1-alpha, tripartite motif-containing protein 24, ring finger protein 82. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: trim24, rnf82, tif1, tif1a. Expressed in: cell-free protein synthesis.
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Resolution:
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2.50Å
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R-factor:
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0.239
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R-free:
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0.285
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Authors:
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S.Kishishita,T.Uchikubo-Kamo,K.Murayama,T.Terada,M.Shirouzu, S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)
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Key ref:
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S.Kishishita
et al.
Crystal sturcture of human bromodomain protein.
To be published,
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Date:
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30-Apr-07
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Release date:
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06-May-08
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PROCHECK
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Headers
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References
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O15164
(TIF1A_HUMAN) -
Transcription intermediary factor 1-alpha from Homo sapiens
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Seq: Struc:
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1050 a.a.
113 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.2.3.2.27
- RING-type E3 ubiquitin transferase.
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Reaction:
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S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N6- ubiquitinyl-[acceptor protein]-L-lysine
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');
}
}
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