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PDBsum entry 2yyn

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protein Protein-protein interface(s) links
Transcription PDB id
2yyn

 

 

 

 

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Contents
Protein chains
113 a.a. *
Waters ×99
* Residue conservation analysis
PDB id:
2yyn
Name: Transcription
Title: Crystal structure of human bromodomain protein
Structure: Transcription intermediary factor 1-alpha. Chain: a, b, c, d. Fragment: bromo domain. Synonym: tif1-alpha, tripartite motif-containing protein 24, ring finger protein 82. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim24, rnf82, tif1, tif1a. Expressed in: cell-free protein synthesis.
Resolution:
2.50Å     R-factor:   0.239     R-free:   0.285
Authors: S.Kishishita,T.Uchikubo-Kamo,K.Murayama,T.Terada,M.Shirouzu, S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)
Key ref: S.Kishishita et al. Crystal sturcture of human bromodomain protein. To be published, .
Date:
30-Apr-07     Release date:   06-May-08    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
O15164  (TIF1A_HUMAN) -  Transcription intermediary factor 1-alpha from Homo sapiens
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
1050 a.a.
113 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.2.3.2.27  - RING-type E3 ubiquitin transferase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N6- ubiquitinyl-[acceptor protein]-L-lysine

 

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