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PDBsum entry 2yy2
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Contents |
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* Residue conservation analysis
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PDB id:
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Hydrolase
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Title:
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Crystal structure of the human phosphodiesterase 9a catalytic domain complexed with ibmx
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Structure:
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High-affinity cgmp-specific 3',5'-cyclic phosphodiesterase 9a. Chain: a, b. Fragment: catalytic domain, unp residues 241-566. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Other_details: e. Coli cell free system
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Resolution:
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2.80Å
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R-factor:
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0.206
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R-free:
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0.240
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Authors:
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N.Handa,M.Shirouzu,T.Terada,K.Omori,J.Kotera,S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)
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Key ref:
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N.Handa
et al.
Crystal structure of the human phosphodiesterase 9a catalytic domain.
To be published,
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Date:
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27-Apr-07
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Release date:
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30-Oct-07
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PROCHECK
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Headers
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References
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O76083
(PDE9A_HUMAN) -
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A from Homo sapiens
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Seq:
Struc:
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593 a.a.
326 a.a.
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Key: |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.3.1.4.35
- 3',5'-cyclic-GMP phosphodiesterase.
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Reaction:
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3',5'-cyclic GMP + H2O = GMP + H+
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3',5'-cyclic GMP
Bound ligand (Het Group name = )
matches with 50.00% similarity
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+
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H2O
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=
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GMP
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+
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H(+)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
