PDBsum entry 2yvr

Metal binding protein

PDB id: 2yvr

Contents

Protein chains

45 a.a. *

Metals

_ZN ×4

Waters ×95

* Residue conservation analysis

PDB id:

2yvr

Name:

Metal binding protein

Title:

Crystal structure of ms1043

Structure:

Transcription intermediary factor 1-beta. Chain: a, b. Fragment: zf-b_box domain, residues in database 201-250. Synonym: ms1043, tif1-beta, tripartite motif-containing protein 28, nuclear corepressor kap-1, krab- associated protein 1, kap-1, krab- interacting protein 1, krip-1, ring finger protein 96. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Other_details: cell-free protein synthesis

Resolution:

1.80Å R-factor: 0.187 R-free: 0.218

Authors:

H.Wang,S.Kishishita,K.Murayama,C.Takemoto,T.Terada,M.Shirouzu,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

H.Wang et al. Crystal structure of ms1043. To be published, .

Date:

13-Apr-07 Release date: 15-Apr-08

Protein chains

Q13263  (TIF1B_HUMAN) -  Transcription intermediary factor 1-beta from Homo sapiens

Seq: 835 a.a.

Struc: 45 a.a.

Enzyme reactions

• Enzyme class: E.C.2.3.2.27 - RING-type E3 ubiquitin transferase.
• Reaction: S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N₆- ubiquitinyl-[acceptor protein]-L-lysine