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UniProt functional annotation for Q8VCZ6 | ||
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| UniProt code: Q8VCZ6. |
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| Organism: | |
Mus musculus (Mouse). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus. |
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| Function: | |
May play a cooperative role in NF2-mediated growth suppression of cells. {ECO:0000250}. |
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| Subunit: | |
Interacts with GJA1. Interaction with GJA1 induces its degradation. Interacts via its RUN domain with the C-terminal region of NF2. Interacts with RAB3A, RAB4A, RAB5A, RAB8A, RAB11A, RAP1A, RAP1B, RAP2A, RAP2B and PDCD6I. No interaction with RAB27A (By similarity). {ECO:0000250|UniProtKB:Q96HU1, ECO:0000269|PubMed:15709751}. |
| Subcellular location: | |
Cytoplasm {ECO:0000250|UniProtKB:Q96HU1}. |
| Tissue specificity: | |
Widely expressed. {ECO:0000269|PubMed:17509819}. |
| Similarity: | |
Belongs to the small G protein signaling modulator family. {ECO:0000305}. |
| Sequence caution: | |
Sequence=BAE42041.1; Type=Erroneous initiation; Evidence={ECO:0000305}; |
Annotations taken from UniProtKB at the EBI.