UniProt functional annotation for P43596

UniProt code: P43596.

Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Taxonomy: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
 
Function: Functions as component of the ISW1A complex, which acts in remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. The ISW1A complex represses gene expression at initiation through specific positioning of a promoter proximal dinucleosome. {ECO:0000269|PubMed:12482963, ECO:0000269|PubMed:14622597}.
 
Subunit: Component of the ISW1A complex, which at least consists of ISW1 and IOC3. {ECO:0000269|PubMed:12482963}.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}.
Miscellaneous: Present with 1770 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.

Annotations taken from UniProtKB at the EBI.