 |
PDBsum entry 2y9t
|
|
|
|
PDB id:
|
|
|
|
| Name: |
|
Apoptosis
|
|
|
Title:
|
|
Structural basis of p63a sam domain mutants involved in aec syndrome
|
|
Structure:
|
|
Tumor protein 63. Chain: a. Fragment: sam domain, residues 543-622. Synonym: chronic ulcerative stomatitis protein, keratinocyte transcription factor ket, transformation-related protein 63, tumor protein p73-like, p40, p51, p63, cusp, tp63, p73l. Engineered: yes
|
|
Source:
|
|
Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: c41.
|
|
NMR struc:
|
|
20 models
|
|
|
Authors:
|
|
A.Sathyamurthy,S.M.V.Freund,C.M.Johnson,M.D.Allen
|
|
Key ref:
|
|
A.Sathyamurthy
et al.
(2011).
Structural basis of p63α SAM domain mutants involved in AEC syndrome.
Febs J,
278,
2680-2688.
PubMed id:
|
|
|
Date:
|
|
|
16-Feb-11
|
Release date:
|
03-Aug-11
|
|
|
|
|
|
|
PROCHECK
|
|
|
|
|
|
Headers
|
|
|
|
References
|
|
|
|
|
|
|
|
Q9H3D4
(P63_HUMAN) -
Tumor protein 63 from Homo sapiens
|
|
|
|
Seq:
Struc:
|
|
|
|
680 a.a.
82 a.a.*
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Key: |
 |
PfamA domain |
|
|
 |
Secondary structure |
|
 |
CATH domain |
|
|
*
PDB and UniProt seqs differ
at 2 residue positions (black
crosses)
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
|
|
|
|
|
|
| |
|
|
Febs J
278:2680-2688
(2011)
|
|
PubMed id:
|
|
|
|
|
|
| |
|
Structural basis of p63α SAM domain mutants involved in AEC syndrome.
|
|
A.Sathyamurthy,
S.M.Freund,
C.M.Johnson,
M.D.Allen,
M.Bycroft.
|
|
|
|
|
| |
ABSTRACT
|
|
|
|
| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
 |
 |
|
Links
