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PDBsum entry 2xxy

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protein ligands Protein-protein interface(s) links
Transport protein PDB id
2xxy

 

 

 

 

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Contents
Protein chains
248 a.a. *
Ligands
KAI ×4
* Residue conservation analysis
PDB id:
2xxy
Name: Transport protein
Title: Crystal structure of the gluk2 (glur6) d776k lbd dimer in complex with kainate
Structure: Glutamate receptor, ionotropic kainate 2. Chain: a, b, c, d. Fragment: ligand binding domain, residues 429-544,667-806. Synonym: glutamate receptor 6, glur-6, glur6. Engineered: yes. Mutation: yes
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Resolution:
3.00Å     R-factor:   0.224     R-free:   0.264
Authors: N.Nayeem,O.Mayans,T.Green
Key ref: N.Nayeem et al. (2011). Conformational flexibility of the ligand-binding domain dimer in kainate receptor gating and desensitization. J Neurosci, 31, 2916-2924. PubMed id: 21414913
Date:
12-Nov-10     Release date:   09-Feb-11    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P42260  (GRIK2_RAT) -  Glutamate receptor ionotropic, kainate 2 from Rattus norvegicus
Seq:
Struc:
 
Seq:
Struc:
908 a.a.
248 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Enzyme reactions 
   Enzyme class: E.C.?
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

 

 
J Neurosci 31:2916-2924 (2011)
PubMed id: 21414913  
 
 
Conformational flexibility of the ligand-binding domain dimer in kainate receptor gating and desensitization.
N.Nayeem, O.Mayans, T.Green.
 
  ABSTRACT  
 
No abstract given.

 

 

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