PDBsum entry 2xp2

Transferase

PDB id: 2xp2

Contents

Protein chain

289 a.a.

Ligands

VGH

Waters ×167

References listed in PDB file

Key reference

• Title: Structure based drug design of crizotinib (pf-02341066), A potent and selective dual inhibitor of mesenchymal-Epithelial transition factor (c-Met) kinase and anaplastic lymphoma kinase (alk).
• Authors: J.J.Cui, M.Tran-Dubé, H.Shen, M.Nambu, P.P.Kung, M.Pairish, L.Jia, J.Meng, L.Funk, I.Botrous, M.Mctigue, N.Grodsky, K.Ryan, E.Padrique, G.Alton, S.Timofeevski, S.Yamazaki, Q.Li, H.Zou, J.Christensen, B.Mroczkowski, S.Bender, R.S.Kania, M.P.Edwards.
• Ref.: J Med Chem, 2011, 54, 6342-6363.
• PubMed id: 21812414

Abstract

No abstract given.