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PDBsum entry 2xjz
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125 a.a.
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112 a.a.
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29 a.a.
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31 a.a.
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21 a.a.
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26 a.a.
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* Residue conservation analysis
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PDB id:
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Oncoprotein
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Title:
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Crystal structure of the lmo2:ldb1-lid complex, c2 crystal form
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Structure:
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Rhombotin-2. Chain: a, b, c, d, e. Fragment: residues 26-156. Synonym: lim domain only protein 2, cysteine-rich protein ttg-2, t- cell translocation protein 2, lmo-2. Engineered: yes. Lim domain-binding protein 1. Chain: i, j, k, l, m. Fragment: residues 334-368.
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
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Resolution:
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2.80Å
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R-factor:
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0.229
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R-free:
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0.244
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Authors:
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K.El Omari,D.Karia,C.Porcher,E.J.Mancini
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Key ref:
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K.El Omari
et al.
(2011).
Structure of the leukemia oncogene LMO2: implications for the assembly of a hematopoietic transcription factor complex.
Blood,
117,
2146-2156.
PubMed id:
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Date:
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06-Jul-10
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Release date:
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21-Jul-10
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PROCHECK
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Headers
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References
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P25791
(RBTN2_HUMAN) -
Rhombotin-2 from Homo sapiens
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Seq: Struc:
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158 a.a.
125 a.a.
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P25791
(RBTN2_HUMAN) -
Rhombotin-2 from Homo sapiens
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Seq: Struc:
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158 a.a.
112 a.a.*
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Q86U70
(LDB1_HUMAN) -
LIM domain-binding protein 1 from Homo sapiens
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Seq: Struc:
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411 a.a.
29 a.a.
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Q86U70
(LDB1_HUMAN) -
LIM domain-binding protein 1 from Homo sapiens
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Seq: Struc:
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411 a.a.
31 a.a.*
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Blood
117:2146-2156
(2011)
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PubMed id:
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Structure of the leukemia oncogene LMO2: implications for the assembly of a hematopoietic transcription factor complex.
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K.El Omari,
S.J.Hoosdally,
K.Tuladhar,
D.Karia,
P.Vyas,
R.Patient,
C.Porcher,
E.J.Mancini.
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ABSTRACT
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Literature references that cite this PDB file's key reference
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PubMed id
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Reference
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J.M.Matthews,
K.Lester,
S.Joseph,
and
D.J.Curtis
(2012).
LIM-domain-only proteins in cancer.
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Nat Rev Cancer,
13,
111-122.
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The most recent references are shown first.
Citation data come partly from CiteXplore and partly
from an automated harvesting procedure. Note that this is likely to be
only a partial list as not all journals are covered by
either method. However, we are continually building up the citation data
so more and more references will be included with time.
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}
}
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