PDBsum entry 2xa4

Transferase

PDB id: 2xa4

Contents

Protein chain

278 a.a.

Ligands

AZ5 ×2

Waters ×308

References listed in PDB file

Key reference

• Title: Discovery of 5-Chloro-N2-[(1s)-1-(5-Fluoropyrimidin-2-Yl)ethyl]-N4-(5-Methyl-1h-Pyrazol-3-Yl)pyrimidine-2,4-Diamine (azd1480) as a novel inhibitor of the jak/stat pathway.
• Authors: S.Ioannidis, M.L.Lamb, T.Wang, L.Almeida, M.H.Block, A.M.Davies, B.Peng, M.Su, H.J.Zhang, E.Hoffmann, C.Rivard, I.Green, T.Howard, H.Pollard, J.Read, M.Alimzhanov, G.Bebernitz, K.Bell, M.Ye, D.Huszar, M.Zinda.
• Ref.: J Med Chem, 2011, 54, 262-276.
• PubMed id: 21138246

Abstract

No abstract given.