PDBsum entry 2x51

Motor protein/signaling protein

PDB id: 2x51

Contents

Protein chains

737 a.a. *

146 a.a. *

Ligands

GOL ×7

SO4

Metals

_CA ×3

Waters ×251

* Residue conservation analysis

PDB id:

2x51

Name:

Motor protein/signaling protein

Title:

M6 delta insert1

Structure:

Myosin-vi. Chain: a. Fragment: myosin vi delta insert1,residues 1-277,303-817. Synonym: unconventional myosin vi. Engineered: yes. Calmodulin. Chain: b. Synonym: cam. Engineered: yes

Source:

Sus scrofa. Pig. Organism_taxid: 9823. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Expression_system_taxid: 7108

Resolution:

2.20Å R-factor: 0.219 R-free: 0.272

Authors:

G.Squires,A.Houdusse

Key ref:

O.Pylypenko et al. (2011). Role of insert-1 of myosin VI in modulating nucleotide affinity. J Biol Chem, 286, 11716-11723. PubMed id: 21278381

Date:

04-Feb-10 Release date: 26-Jan-11

Protein chain

Q29122  (MYO6_PIG) -  Unconventional myosin-VI from Sus scrofa

Seq: 1254 a.a.

Struc: 737 a.a.*

Protein chain

P62152  (CALM_DROME) -  Calmodulin from Drosophila melanogaster

Seq: 149 a.a.

Struc: 146 a.a.

* PDB and UniProt seqs differ at 6 residue positions (black crosses)

J Biol Chem 286:11716-11723 (2011)

PubMed id: 21278381

Role of insert-1 of myosin VI in modulating nucleotide affinity.

O.Pylypenko, L.Song, G.Squires, X.Liu, A.B.Zong, A.Houdusse, H.L.Sweeney.

ABSTRACT

No abstract given.