UniProt functional annotation for Q04756

UniProt code: Q04756.

Organism: Homo sapiens (Human).
Taxonomy: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
 
Function: Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form.
 
Subunit: Heterodimer of a short chain and a long chain linked by a disulfide bond. {ECO:0000269|PubMed:15713485, ECO:0000269|PubMed:18077410}.
Subcellular location: Secreted. Note=Secreted as an inactive single- chain precursor and is then activated to a heterodimeric form.
Tissue specificity: Liver.
Similarity: Belongs to the peptidase S1 family. {ECO:0000255|PROSITE- ProRule:PRU00274}.

Annotations taken from UniProtKB at the EBI.